Sander Peter, Alcaide Fernando, Richter Ingeborg, Frischkorn Klaus, Tortoli Enrico, Springer Burkhard, Telenti Amalio, Böttger Erik C
Institut für Medizinische Mikrobiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Département de Medicine Interne, Division des Maladies Infectieuses, CHUV-1011 Lausanne, Switzerland.
Microbiology (Reading). 1998 Feb;144 ( Pt 2):589-591. doi: 10.1099/00221287-144-2-589.
The A subunit of DNA gyrase in mycobacteria is frequently subjected to splicing events as its gene, gyrA, harbours an insertion encoding an intein. Investigation of a number of different isolates of Mycobacterium kansasii, Mycobacterium malmoense, Mycobacterium marinum, Mycobacterium ulcerans and Mycobacterium xenopi demonstrated that the presence of GyrA inteins is not random but a taxonomic character specific for a given taxon at a species or subspecies level.
分枝杆菌中DNA促旋酶的A亚基经常发生剪接事件,因为其基因gyrA含有一个编码内含肽的插入序列。对堪萨斯分枝杆菌、马尔默分枝杆菌、海分枝杆菌、溃疡分枝杆菌和偶发分枝杆菌的多个不同分离株进行研究表明,GyrA内含肽的存在并非随机现象,而是在物种或亚种水平上特定分类群的一个分类学特征。