Russo F, Marci M, Raffa S
Divisione di Medicina Generale, A.S.L. RM/G-Ospedale Angelucci, Subiaco.
Clin Ter. 1997 Nov;148(11):537-41.
The Authors report, in this article, about pathophysiology mechanism that is to the base of the vascular injury mediate from the Angiotensin II able of modulate the primer, the acceleration and the progression of the atherosclerosis. Afterward is considered the importance of the administration of the inhibiting of the receptors AT-1 (Losartan) in the control of the hypertension and of the atherosclerosis.
作者在本文中报告了血管损伤的病理生理机制,该机制是由能够调节动脉粥样硬化起始、加速和进展的血管紧张素II介导的。随后,探讨了给予AT-1受体抑制剂(氯沙坦)在控制高血压和动脉粥样硬化方面的重要性。