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[F2 后代数量性状主基因-多基因混合遗传模型的鉴定及遗传参数估计]

[Identification of major gene and polygene mixed inheritance model and estimation of genetic parameters of a quantitative trait from F2 progeny].

作者信息

Wang J, Gai J

机构信息

Soybean Research Institute, Nanjing Agricultural University.

出版信息

Yi Chuan Xue Bao. 1997 Oct;24(5):432-40.

PMID:9494295
Abstract

It has been proved by many field experiments and QTL mapping results that among genes affecting some quantitative traits there are some major genes with larger genetic effect and some polygenes with smaller genetic effect. For such traits, the distribution of segregating population demonstrates multimodality, and this is the characteristic of the mixture of more than one distributions. Mixture distribution models have been used extensively as models in a wide variety of practical situations where data can be viewed as arising from two or more populations mixed in certain proportions. Akaike's Information Criterion(AIC) has been used to identify the existence of major genes affecting quantitative traits. Under the existence of major genes, the genetic effects of these genes and their genetic variance were estimated through segregation analysis. The genotype of major gene of F2 individuals of were determined by clustering using Bayesian criterion. With P1, P2, F1 and F2 populations, the likelihood ratio test was used to test the existence of polygenes. In the end, the inheritance of soybean flowering date is analyzed. One major gene was found in F2 population derived from Guludou x Shanghaihongmangzao.

摘要

许多田间试验和QTL定位结果已证明,在影响某些数量性状的基因中,存在一些遗传效应较大的主基因和一些遗传效应较小的多基因。对于这类性状,分离群体的分布呈现多峰性,这是多种分布混合的特征。混合分布模型已在广泛的实际情况中被广泛用作模型,在这些情况下,数据可被视为由按一定比例混合的两个或多个群体产生。赤池信息准则(AIC)已被用于识别影响数量性状的主基因的存在。在主基因存在的情况下,通过分离分析估计这些基因的遗传效应及其遗传方差。利用贝叶斯准则通过聚类确定F2个体主基因的基因型。利用P1、P2、F1和F2群体,采用似然比检验来检验多基因的存在。最后,对大豆开花期的遗传进行了分析。在源自古鲁豆×上海红芒早的F2群体中发现了一个主基因。

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