Vázquez-Gutiérrez T, Sánchez-Valderrábanos J, Caba-Barrientos F
Servicio de Anestesiología, Hospital Universitario de Valme, Sevilla.
Rev Esp Anestesiol Reanim. 1997 Dec;44(10):396-407.
Adult sleep apnea syndrome is a common condition characterized by repeated apneic events during sleep, producing hypoxia, a potentially neurovegetative response and loss of normal sleep structure. Important pathophysiological repercussions can ensue. Adults with sleep apnea syndrome have particular upper airway sensitivity to sedatives, muscle relaxants, anesthetic agents and narcotic analgesics, potentially compromising the anesthetic management of such patients, among whom serious respiratory complications have been reported. This review describes current data for prevalence, etiopathogenesis, pathophysiological consequences, and the diagnosis and treatment of various forms of the syndrome. Also described is the approach to anesthetic care before, during and after surgery related to the specific condition or not.
成人睡眠呼吸暂停综合征是一种常见病症,其特征为睡眠期间反复出现呼吸暂停事件,会导致缺氧、潜在的自主神经反应以及正常睡眠结构丧失。随之可能产生重要的病理生理影响。患有睡眠呼吸暂停综合征的成年人对上呼吸道镇静剂、肌肉松弛剂、麻醉剂和麻醉性镇痛药具有特殊敏感性,这可能会影响此类患者的麻醉管理,据报道这类患者中会出现严重的呼吸并发症。本综述介绍了该综合征各种形式的患病率、病因发病机制、病理生理后果以及诊断和治疗的当前数据。还介绍了与该特定病症相关或不相关的手术前、手术中和手术后的麻醉护理方法。