喹啉酸：对大鼠下丘脑弓状核的影响（超微结构证据）
Quinolinic acid: effect on the nucleus arcuatus of the hypothalamus in the rat (ultrastructural evidence).
作者信息
Beskid M, Rózycka Z, Taraszewska A
机构信息
Medical Centre of Postgraduate Education, Laboratory of Histochemistry, Warsaw, Poland.
出版信息
Exp Toxicol Pathol. 1997 Dec;49(6):477-81. doi: 10.1016/S0940-2993(97)80141-8.
PMID:9495649
Abstract
Quinolinic acid was administered intraperitoneally to male Wistar rats in a dose of 60 mmol, once daily for 8 days. By electron microscopy, in quinolinic acid-treated rats, the neuronal cell bodies in the arcuate nucleus had features of increased cellular activity, but some damage of neuronal cell bodies was also evident.
摘要
以60毫摩尔的剂量将喹啉酸腹腔注射给雄性Wistar大鼠，每天一次，持续8天。通过电子显微镜观察，在接受喹啉酸治疗的大鼠中，弓状核中的神经元细胞体具有细胞活性增加的特征，但神经元细胞体的一些损伤也很明显。
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