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南威尔士水中的微量元素与中枢神经系统先天性畸形

Trace elements in water and congenital malformations of the central nervous system in South Wales.

作者信息

Morton M S, Elwood P C, Abernethy M

出版信息

Br J Prev Soc Med. 1976 Mar;30(1):36-9. doi: 10.1136/jech.30.1.36.

DOI:10.1136/jech.30.1.36
PMID:949571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC478936/
Abstract

The concentrations of 20 trace elements were determined by atomic absorption spectrophotometry on representative samples of tap-water collected from 48 local authority areas in South Wales. The associations between twelve trace elements and central nervous system (CNS) malformation rates for the 48 areas were examined. Significant correlations for four trace elements were observed. Of these, Al was positively correlated while for the remaining three-Ca, Ba, and Cu-negative associations were found. Regression analysis of the data suggested that the relationships between Ba and Cu with CNS malformation rates were improtant than those of Al and Ca.

摘要

采用原子吸收分光光度法对从南威尔士48个地方当局区域采集的自来水代表性样本中的20种微量元素浓度进行了测定。研究了这48个区域中12种微量元素与中枢神经系统(CNS)畸形率之间的关联。观察到4种微量元素存在显著相关性。其中,铝呈正相关,而其余3种元素——钙、钡和铜——呈负相关。数据的回归分析表明,钡和铜与中枢神经系统畸形率之间的关系比铝和钙的关系更为重要。

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