Van der Laarse R, Strackee J
Br J Radiol. 1976 May;49(581):450-7. doi: 10.1259/0007-1285-49-581-450.
A chain consisting of three computer programs has been developed for treatment planning of external beam radiotherapy without manual intervention. Apart from the data necessary to identify the patient, the institute, etc., the input consists only of the anatomical information indicated on an outline sheet. Firstly, combinations of incidence directions for a two or three-beam set-up are judged by the first program. Then a limited number of these combinations is selected by this program. For every beam of each selected combination a set of wedges and weights is calculated. Next the dose distributions belonging to each combination with wedges and weights are judged by the second program. Finally, the isodose pattern of the dose distribution judged the best is determined by the third program. The judgement of incidence directions is done by coarse score functions corresponding to a set of criteria. The judgement of dose distribution is done by detailed score functions corresponding to another set of criteria. These criteria with their score functions are treated in some detail. The use of the programs in the clinic is discusses and results are shown.
已经开发了一个由三个计算机程序组成的链,用于在无需人工干预的情况下进行外照射放疗的治疗计划。除了识别患者、机构等所需的数据外,输入仅包括轮廓图上所示的解剖信息。首先,第一个程序判断两束或三束设置的入射方向组合。然后该程序选择这些组合中的有限数量。对于每个选定组合的每束射线,计算一组楔形板和配重。接下来,第二个程序判断属于每个带有楔形板和配重组合的剂量分布。最后,第三个程序确定被判定为最佳的剂量分布的等剂量模式。入射方向的判断通过与一组标准相对应的粗略评分函数来完成。剂量分布的判断通过与另一组标准相对应的详细评分函数来完成。这些标准及其评分函数将进行详细讨论。文中讨论了这些程序在临床中的应用并展示了结果。