Harf L, Arch S, Eskin A
Brain Res. 1976 Jul 30;111(2):295-9. doi: 10.1016/0006-8993(76)90774-5.
The possibility of neurosecretory activity by the eye of Aplysia californica has been suggested by morphological findings. An investigation was conducted to determine if evidence for the release of macromolecular material labeled with radioactive amino acids could be obtained. Depolarization of the eye by superfusion with medium containing an elevated potassium concentration resulted in a significant increase of labeled macromolecular material in the superfusate. This potassium-induced release could be blocked by reduction of the calcium concentration in the superfusing medium. The locus of release appears to be the eye proper and not to involve the optic nerve.
形态学研究结果提示，加州海兔的眼睛可能存在神经分泌活动。开展了一项研究，以确定是否能够获得用放射性氨基酸标记的大分子物质释放的证据。用含高钾浓度的培养基进行眼灌流使眼睛去极化，导致灌流液中标记大分子物质显著增加。这种钾诱导的释放可通过降低灌流培养基中的钙浓度来阻断。释放部位似乎是眼睛本身，而不涉及视神经。
