Lindinger A, Huhn W
Z Geburtshilfe Perinatol. 1979 Dec;183(6):461-4.
It is reported on a newborn suffering from a pronounced hypothyreosis and a big goitre caused by an amniofetography during the 22. week of pregnancy using a hydrous and a oily iodiferous drug. The big goitre impeded the respiration, so that intubation was indicated. After treatment with thyroid hormones for 8 months the goitre decreased. The thyroid hormone-levels and function tests were in normal range after interruption of the thyroid drugs. Etiology and pathogenesis of this disease are discussed. It is warned of using drugs containing high iodine doses for amnio- or fetography.
据报道,一名新生儿患有明显的甲状腺功能减退症和巨大甲状腺肿,这是由于在妊娠22周时进行羊膜腔造影和胎儿造影时使用了含水和油性含碘药物所致。巨大甲状腺肿阻碍了呼吸,因此需要进行插管。在用甲状腺激素治疗8个月后,甲状腺肿缩小。停用甲状腺药物后,甲状腺激素水平和功能测试均在正常范围内。文中讨论了该疾病的病因和发病机制。同时警告不要在羊膜腔造影或胎儿造影中使用高碘剂量的药物。