de Oliveira C G, Collares E F, Barbieri M A, Fernandes M I
Departamento de Puericultura e Pediatria da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo-FMRP-USP.
Arq Gastroenterol. 1997 Apr-Jun;34(2):105-11.
The objective of the present study was to study the profile of salivary amylase in obese children. The study was conducted on 58 children, 29 of whom were identified as obese (obese group) and 29 as non-obese (control group). The parameters for the assignment to the two groups studied were the W/H ratio of the NCHS and the tricipital skinfold. The children in the obese group presented percentiles of 90 or more for both curves. Saliva was collected after chemical stimulation with lemon juice using a standardized technique. The weight of secreted saliva and the concentration and total production of salivary amylase over a period of five minutes were determined in the samples collected. The results demonstrated that, among the control children, amylase concentration and total production were significantly higher in boys than in girls. Among the obese children, boys presented significantly higher salivary secretion than girls. Obese boys presented a significantly lower amylase concentration compared to control, a fact that was not observed for girls. Total salivary amylase production was not reduced among obese boys, suggesting that the decreased enzyme concentration in obese subjects is compensated for by greater salivary secretion.
本研究的目的是研究肥胖儿童唾液淀粉酶的情况。该研究对58名儿童进行，其中29名被确定为肥胖儿童（肥胖组），29名被确定为非肥胖儿童（对照组）。用于将儿童分配到两组的研究参数是美国国家卫生统计中心（NCHS）的体重/身高比和三头肌皮褶厚度。肥胖组儿童的这两条曲线百分位数均为90或更高。使用标准化技术，在柠檬汁化学刺激后收集唾液。在所收集的样本中，测定了分泌唾液的重量以及五分钟内唾液淀粉酶的浓度和总产量。结果表明，在对照儿童中，男孩的淀粉酶浓度和总产量显著高于女孩。在肥胖儿童中，男孩的唾液分泌显著高于女孩。与对照组相比，肥胖男孩的淀粉酶浓度显著降低，而女孩未观察到这一情况。肥胖男孩的唾液淀粉酶总产量并未降低，这表明肥胖受试者中酶浓度的降低被唾液分泌的增加所补偿。
