儿童头颈部胚胎性横纹肌肉瘤。分期、放射剂量、局部控制与生存的相关性。

Embryonal rhabdomyosarcoma of head and neck in children. Correlation of stage, radiation dose, local control, and survival.

作者信息

Liebner E J

出版信息

Cancer. 1976 Jun;37(6):2777-86. doi: 10.1002/1097-0142(197606)37:6<2777::aid-cncr2820370632>3.0.co;2-s.

DOI:10.1002/1097-0142(197606)37:6<2777::aid-cncr2820370632>3.0.co;2-s

Abstract

Nineteen consecutive children are analyzed according to clinical stay, radiation dose (NSD), local control, and survival. The majority received 1600 to 1750 rets and courses of actinomycin during their radiation treatments. The favorable sites were the orbit, facial soft tissue, and the larynx. The primary site control rate was 89%, and the metastatic neck control rate was 80%. The 2-year survival was 70%, and the 5-year survival was 67%. Five children are alive and well 12 to 15 years after irradiation. Late sequelae are hypoplasia of the orbit and maxillary sinus.

摘要

对19名连续的儿童按照临床住院时间、放射剂量（NSD）、局部控制和生存率进行了分析。大多数儿童在放射治疗期间接受了1600至1750拉德的剂量以及放线菌素疗程。有利部位为眼眶、面部软组织和喉部。原发部位控制率为89%，颈部转移灶控制率为80%。2年生存率为70%，5年生存率为67%。5名儿童在放疗后12至15年仍健在且状况良好。晚期后遗症为眼眶和上颌窦发育不全。