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双开关阀在成人正常血压性或高血压性脑积水治疗中的重要性。

The importance of the dual-switch valve for the treatment of adult normotensive or hypertensive hydrocephalus.

作者信息

Sprung C, Miethke C, Shakeri K, Lanksch W R

机构信息

Neurosurgical Department, Virchow-Klinikum, Humboldt University Berlin, Germany.

出版信息

Eur J Pediatr Surg. 1997 Dec;7 Suppl 1:38-40. doi: 10.1055/s-2008-1071208.

Abstract

Since the beginning of 1995 the new hydrostatic dual-switch valve (DSV) was implanted in 35 adult patients with hydrocephalus of different etiology. 26 patients suffered from normotensive hydrocephalus (10 idiopathic and 16 symptomatic), and 9 patients from hypertensive hydrocephalus of various origin. The first 21 cases of this cohort were compared in a randomized study with a comparable group of 21 hydrocephalic patients who received a conventional differential-pressure (DP-) valve. The clinical status and CT were assessed prior to shunting, 14 days and 3 and 6 months after the operation. The reduction of ventricular size was evaluated by the measurement of the Evans Index. The CT follow-up in the DSV group was characterized by an only minimal (14) or only slight (16) reduction of ventricular size in the vast majority of cases. A comparison of 21 patients with a DSV and the patients with DP valves, evaluated by measuring the reduction of the Evans Index, revealed a distinctly higher percentage of significant regressions in the DP valve collective, without doubt due to chronic overdrainage. The overall clinical result of our 35 patients with a DSV was excellent and good in 31 patients, but the outcome seems to be more dependent on the preshunt damage of the brain than on hydrocephalic aspects. A neglegible incidence of subdural effusions in the DSV group compared to 11 cases in the DP valve collective reflects the ability of the DSV to prevent overdrainage. The capability of the DSV to maintain the IVP within physiological limits after shunting, especially in the upright position, is documented by a comparison with possible unphysiological IVP variations in other valve constructions, which depend on the level of implantation, subcutaneous pressure or CSF flow through the valve.

摘要

自1995年初起,35例不同病因的成年脑积水患者植入了新型静水压双开关阀(DSV)。26例为常压性脑积水(10例特发性和16例症状性),9例为各种原因引起的高压性脑积水。该队列中的前21例患者与21例接受传统压差(DP)阀的脑积水患者进行了随机对照研究。在分流术前、术后14天、3个月和6个月评估临床状态和CT。通过测量埃文斯指数评估脑室大小的缩小情况。DSV组的CT随访显示,绝大多数病例脑室大小仅轻微(14例)或稍有(16例)缩小。通过测量埃文斯指数的降低情况对21例DSV患者和DP阀患者进行比较,发现DP阀组显著缩小的比例明显更高,无疑是由于慢性过度引流所致。我们35例DSV患者的总体临床结果为31例优或良,但结果似乎更多地取决于分流术前的脑损伤,而非脑积水方面。与DP阀组的11例相比,DSV组硬膜下积液的发生率可忽略不计,这反映了DSV预防过度引流的能力。与其他瓣膜结构可能出现的非生理性颅内压变化(取决于植入水平、皮下压力或脑脊液通过瓣膜的流量)相比,DSV在分流后将颅内压维持在生理限度内的能力,尤其是在直立位时,得到了证实。

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