Ayoub M S, Abdel-Salam F M, Abdel-Azim A M
Oral Pathology Depart., Faculty of Oral and Dental Medicine, Cairo University.
Egypt Dent J. 1995 Apr;41(2):1203-9.
Clinical and immunocytochemical analysis of twenty eight cases of giant cell tumour of bone was performed in this study. The results revealed that nine of the cases were benign, while the other nineteen were malignant. The female to male ratio was 2.5:1. The average age incidence was 28.18 years. The most common site of occurrence was the femur. anti endothelial antibody revealed negative immunocytochemical reaction of the stromal cells and giant cells for both benign and malignant cases; While using anti-HLA-DR antibody demonstrated positive immune reaction of some of the strumal and giant cells of all the cases examined.
本研究对28例骨巨细胞瘤进行了临床和免疫细胞化学分析。结果显示，其中9例为良性，其余19例为恶性。男女比例为2.5:1。平均发病年龄为28.18岁。最常见的发病部位是股骨。抗内皮细胞抗体显示，良性和恶性病例的基质细胞和巨细胞免疫细胞化学反应均为阴性；而使用抗HLA-DR抗体时，所有检查病例的部分基质细胞和巨细胞显示阳性免疫反应。
