Dinç H, Esen F, Demirci A, Sari A, Resit Gümele H
Department of Radiology, KTU Medical Faculty, Trabzon, Turkey.
Acta Radiol. 1998 Jan;39(1):64-9. doi: 10.1080/02841859809172152.
Our purpose was to clarify and further characterize the changes in height, length, width, volume, and shape in the normal pituitary gland and in width in the infundibulum during pregnancy and the first 6 months post partum.
Cranial MR imaging was performed in 78 women who were pregnant in the second or third trimester or who were post partum, and in 18 age-matched control subjects who were not pregnant. Volume measurements were performed in 2 ways; volume 1=1/2 x height x length x width; and volume 2=area (measured by trackball) x slice thickness.
Gland volume, height, width, length, and convexity, and infundibular width increased during pregnancy. The highest values were seen during the 3 days immediately post partum. When compared with volunteers, volumes 1 and 2 showed the largest increase (120%) among the parameters. Gland height showed the best correlation (r=0.94, p<0.00001) with gestational age. The mean height of the gland was 8.76 mm in the third trimester. None of the pregnant women had a gland height of above 10 mm during pregnancy. Only 2 subjects had gland heights of 10.04 and 10.2 mm during the 0-3 days post partum. After this first post-partum period of 3 days, the gland size, shape, and volume and the infundibular width returned to normal within 6 months.
The pituitary gland enlarges in three dimensions throughout pregnancy. During pregnancy, the volume of the gland shows the highest percentage of increase compared to its length, height, and width. The maximum height of the gland does not exceed 10 mm during pregnancy but it may exceed 10 mm during the 3 days immediately post partum.
我们的目的是阐明并进一步描述正常垂体在孕期及产后前6个月的高度、长度、宽度、体积和形状的变化，以及漏斗部宽度的变化。
对78名处于妊娠中晚期或产后的女性以及18名年龄匹配的未孕对照者进行头颅磁共振成像检查。体积测量采用两种方法；体积1 = 1/2×高度×长度×宽度；体积2 = （用轨迹球测量的面积）×切片厚度。
孕期垂体体积、高度、宽度、长度及凸度和漏斗部宽度增加。产后立即的3天内数值最高。与志愿者相比，体积1和体积2在各项参数中增加幅度最大（120%）。垂体高度与孕周的相关性最佳（r = 0.94，p < 0.00001）。孕晚期垂体平均高度为8.76毫米。孕期无孕妇垂体高度超过10毫米。产后0 - 3天仅有2名受试者垂体高度分别为10.04毫米和10.2毫米。产后3天这一时期过后，垂体大小、形状和体积以及漏斗部宽度在6个月内恢复正常。
整个孕期垂体在三维方向上增大。孕期垂体体积相较于长度、高度和宽度增加的百分比最高。孕期垂体最大高度不超过10毫米，但产后立即的3天内可能超过10毫米。
