Deodhare S S, Ang L C, Bilbao J M
Department of Pathology, St Michael's Hospital, University of Toronto, Ontario, Canada.
Arch Pathol Lab Med. 1998 Feb;122(2):161-5.
Rosai-Dorfman disease is an idiopathic histiocytic disorder of lymph nodes and extranodal sites. Central nervous system manifestations of this disease are rare, and to our knowledge only 16 cases of intracranial involvement have been reported previously. Intracranial Rosai-Dorfman disease clinically and radiologically resembles meningioma, and histologic examination is essential for a definitive diagnosis. We report two cases of isolated, intracranial, dural-based Rosai-Dorfman disease, review the literature, and discuss the differential diagnoses of this lesion.
罗萨伊-多夫曼病是一种累及淋巴结和结外部位的特发性组织细胞疾病。该疾病的中枢神经系统表现较为罕见，据我们所知，此前仅有16例颅内受累的病例报道。颅内罗萨伊-多夫曼病在临床和影像学上与脑膜瘤相似，组织学检查对于明确诊断至关重要。我们报告2例孤立性、颅内、硬膜型罗萨伊-多夫曼病病例，回顾相关文献，并讨论该病变的鉴别诊断。
