Department of Neurology, The Chinese People's Liberation Army (PLA) General Hospital, 28 Fuxing Road, Hai Dian District, Beijing 100853, China.
J Clin Neurosci. 2010 Oct;17(10):1286-8. doi: 10.1016/j.jocn.2010.01.048.
Sinus histiocytosis with massive lymphadenopathy (SHML), also known as Rosai-Dorfman disease (RDD), is an idiopathic histiocytic disorder of lymph nodes and extranodal sites. Central nervous system (CNS) manifestations, particularly in the absence of nodal disease, are rare. Intracranial RDD clinically and radiologically resembles meningioma, and histologic examination is essential for a definitive diagnosis. We report four patients with RDD primary to the CNS without evidence of other sites of involvement, review the literature, and discuss the clinical manifestations, pathology, treatment and outcome.
窦组织细胞增生伴巨大淋巴结病（SHML），又称罗-道氏病（RDD），是一种特发性淋巴结和结外组织的组织细胞疾病。中枢神经系统（CNS）表现，特别是在无淋巴结疾病的情况下，较为罕见。颅内 RDD 在临床上和影像学上类似于脑膜瘤，组织学检查对明确诊断至关重要。我们报告了 4 例 CNS 原发性 RDD 患者，无其他部位受累的证据，复习文献，并讨论其临床表现、病理学、治疗和预后。
