Mills C M, Lanigan S W, Hughes J, Anstey A V
Department of Dermatology, Bridgend General Hospital, Wales, UK.
Clin Exp Dermatol. 1997 Jul;22(4):166-8.
All patients with port wine stains (PWS) attending a tunable dye laser clinic were examined by one author (SWL), forming a large group which has allowed study of the demographic data of such patients. Two hundred and eighty-three patients, 217 females (median age 24 years, range 0.5-73) and 66 males (median age 20 years, range 0.75-72), were examined. The PWS were on the face in 226, neck in 69, trunk in 36, upper limb in 35 and lower limb in 29. The commonest lesional colour was purple (63 patients), while 39 naevi were pink/red, 35 pink/ purple and 35 pink. The naevus was flat in 255 patients, cobblestoned in 28, associated with hypertrophy in 31 and with scarring in 22. Seventy-two patients (25.4%) had a positive family history of birthmarks, 20 strawberry haemangiomas and 22 PWS, the family history of PWS being higher than expected for the prevalence of this naevus in the population. One hundred and forty-six patients were also examined for naevus anaemicus which was noted in 12 (8.2%), confirming an association between these two naevi. Ninety-four patients had received previous treatment, most commonly with the argon laser (56 patients), of whom only five reported a good result, and 17 of 22 patients with treatment-related scarring had been treated with this laser. Cosmetic camouflage was used in 109 (38.5%) of patients, who usually had PWS on the face (94%), of whom only 46 (16%) had received advice of its use.
所有前往可调染料激光诊所就诊的葡萄酒色斑(PWS)患者均由一位作者(SWL)进行检查,形成了一个庞大的群体,这使得对这类患者的人口统计学数据进行研究成为可能。共检查了283例患者,其中女性217例(中位年龄24岁,范围0.5 - 73岁),男性66例(中位年龄20岁,范围0.75 - 72岁)。葡萄酒色斑位于面部的有226例,颈部69例,躯干36例,上肢35例,下肢29例。最常见的皮损颜色是紫色(63例患者),而39个痣为粉红色/红色,35个为粉红色/紫色,35个为粉红色。255例患者的痣扁平,28例呈鹅卵石样,31例伴有肥大,22例伴有瘢痕形成。72例患者(25.4%)有胎记家族史,其中20例为草莓状血管瘤,22例为葡萄酒色斑,葡萄酒色斑的家族史高于该痣在人群中的患病率预期。还对146例患者进行了贫血痣检查,其中12例(8.2%)发现有贫血痣,证实了这两种痣之间存在关联。94例患者曾接受过先前治疗,最常见的是使用氩激光(56例患者),其中只有5例报告效果良好,在22例有治疗相关瘢痕的患者中,有17例接受过这种激光治疗。109例(38.5%)患者使用了美容遮瑕,这些患者通常面部有葡萄酒色斑(94%),其中只有46例(16%)曾得到过使用美容遮瑕的建议。