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Bleomycin hydrolase is associated with risk of sporadic Alzheimer's disease.

作者信息

Montoya S E, Aston C E, DeKosky S T, Kamboh M I, Lazo J S, Ferrell R E

出版信息

Nat Genet. 1998 Mar;18(3):211-2. doi: 10.1038/ng0398-211.

DOI:10.1038/ng0398-211
PMID:9500538
Abstract
摘要

相似文献

1
Bleomycin hydrolase is associated with risk of sporadic Alzheimer's disease.博来霉素水解酶与散发性阿尔茨海默病的风险相关。
Nat Genet. 1998 Mar;18(3):211-2. doi: 10.1038/ng0398-211.
2
Analysis of association between bleomycin hydrolase and apolipoprotein E polymorphism in Alzheimer's disease.阿尔茨海默病中博来霉素水解酶与载脂蛋白 E 多态性的相关性分析。
Neurol Sci. 2010 Dec;31(6):687-91. doi: 10.1007/s10072-010-0234-4. Epub 2010 Mar 3.
3
Polymorphisms of the human apolipoprotein E promoter and bleomycin hydrolase gene: risk factors for Alzheimer's dementia?人类载脂蛋白E启动子和博来霉素水解酶基因的多态性：阿尔茨海默病性痴呆的危险因素？
Neurosci Lett. 1999 Oct 15;274(1):37-40. doi: 10.1016/s0304-3940(99)00662-x.
4
Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Ann Neurol. 1998 Nov;44(5):808-11. doi: 10.1002/ana.410440515.
5
[Apolipoprotein E and bleomycin hydrolase. Polymorphisms: association with neurodegenerative diseases].[载脂蛋白E与博来霉素水解酶。多态性：与神经退行性疾病的关联]
Ann Biol Clin (Paris). 2003 Jan-Feb;61(1):61-7.
6
Lack of association between bleomycin hydrolase gene polymorphism and Alzheimer's disease in Japanese people.
Ann Neurol. 1999 Jul;46(1):136-7. doi: 10.1002/1531-8249(199907)46:1<136::aid-ana25>3.0.co;2-m.
7
Enzyme that detoxifies cancer drug linked to risk of Alzheimer's disease.
Oncology (Williston Park). 1998 May;12(5):777.
8
Polymorphism of the regulatory region of the presenilin-2 gene in sporadic Alzheimer's disease: a case-control study.散发性阿尔茨海默病中早老素-2基因调控区的多态性：一项病例对照研究。
J Neurol Sci. 2006 Jan 15;240(1-2):71-5. doi: 10.1016/j.jns.2005.09.004. Epub 2005 Oct 17.
9
SREBP-1a polymorphism influences the risk of Alzheimer's disease in carriers of the ApoE4 allele.固醇调节元件结合蛋白-1a基因多态性影响载脂蛋白E4等位基因携带者患阿尔茨海默病的风险。
Dement Geriatr Cogn Disord. 2004;18(3-4):245-9. doi: 10.1159/000080023. Epub 2004 Jul 29.
10
No association of the -48CT polymorphism of the presenilin 1 gene with Alzheimer disease in a late-onset sporadic population.在晚发型散发性人群中，早老素1基因-48CT多态性与阿尔茨海默病无关联。
J Neural Transm (Vienna). 2002 Jul;109(7-8):1023-7. doi: 10.1007/s007020200085.

引用本文的文献

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Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer's Disease.同型半胱氨酸硫内酯解毒酶与阿尔茨海默病。
Int J Mol Sci. 2024 Jul 25;25(15):8095. doi: 10.3390/ijms25158095.
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Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer's Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer's Disease.在 5xFAD 阿尔茨海默病模型小鼠中敲除同型半胱氨酸硫内酯解毒酶博来霉素水解酶导致记忆和神经功能缺陷，并加重阿尔茨海默病相关的行为和生化特征。
J Alzheimers Dis. 2023;95(4):1735-1755. doi: 10.3233/JAD-230578.
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Design and Synthesis of Activity-Based Probes and Inhibitors for Bleomycin Hydrolase.
博来霉素水解酶基于活性的探针和抑制剂的设计与合成
Chem Biol. 2015 Aug 20;22(8):995-1001. doi: 10.1016/j.chembiol.2015.07.010. Epub 2015 Aug 6.
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Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase.人伐昔洛韦水解酶/联苯水解酶样蛋白是一种高效的同型半胱氨酸硫内酯酶。
PLoS One. 2014 Oct 15;9(10):e110054. doi: 10.1371/journal.pone.0110054. eCollection 2014.
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Some evolutionary perspectives on Alzheimer's disease pathogenesis and pathology.阿尔茨海默病发病机制和病理学的一些进化观点。
Alzheimers Dement. 2012 Jul;8(4):343-51. doi: 10.1016/j.jalz.2011.05.2408. Epub 2011 Dec 3.
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A computational framework discovers new copy number variants with functional importance.一个计算框架发现了具有功能重要性的新拷贝数变异。
PLoS One. 2011 Mar 29;6(3):e17539. doi: 10.1371/journal.pone.0017539.
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Analysis of association between bleomycin hydrolase and apolipoprotein E polymorphism in Alzheimer's disease.阿尔茨海默病中博来霉素水解酶与载脂蛋白 E 多态性的相关性分析。
Neurol Sci. 2010 Dec;31(6):687-91. doi: 10.1007/s10072-010-0234-4. Epub 2010 Mar 3.
8
Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase.缺乏中性半胱氨酸蛋白酶博来霉素水解酶的小鼠中的星形胶质细胞增生和行为变化。
Neuroscience. 2007 May 25;146(3):890-900. doi: 10.1016/j.neuroscience.2007.02.027. Epub 2007 Mar 27.
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Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure.木瓜蛋白酶家族蛋白酶博来霉素水解酶催化残基的诱变与晶体学研究：活性位点结构的新见解
Biochem J. 2007 Jan 15;401(2):421-8. doi: 10.1042/BJ20060641.
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Intracellular A-beta amyloid, a sign for worse things to come?细胞内β-淀粉样蛋白，是否预示着更糟糕的情况即将到来？
Mol Neurobiol. 2002 Oct-Dec;26(2-3):299-316. doi: 10.1385/MN:26:2-3:299.