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Ribbons.丝带。
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Molecular biology of vertebrate transcription factor IIIA: cloning and characterization of TFIIIA from channel catfish oocytes.脊椎动物转录因子IIIA的分子生物学：斑点叉尾鮰卵母细胞中TFIIIA的克隆与特性分析
Gene. 1997 Dec 12;203(2):103-12. doi: 10.1016/s0378-1119(97)00499-x.
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Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity.与同源DNA序列结合的TFIIIA前三个锌指的溶液结构：亲和力和序列特异性的决定因素
J Mol Biol. 1997 Oct 17;273(1):183-206. doi: 10.1006/jmbi.1997.1291.
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Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA.TFIIIA N 端锌指结构域在 DNA 复合物中的结构组装与动力学
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A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites.为不同DNA靶位点选择高亲和力锌指蛋白的通用策略。
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Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator.与腺相关病毒P5起始子结合的YY1共晶体结构。
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Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions.锌指蛋白268（Zif268）与DNA复合物在1.6埃分辨率下的结构精修：理解锌指与DNA相互作用的模型系统
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Transcription factor IIIA (TFIIIA) in the second decade.转录因子IIIA（TFIIIA）在第二个十年。
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锌指在DNA识别中的不同作用：一种六指转录因子IIIA复合物的结构

Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex.

作者信息

Nolte R T, Conlin R M, Harrison S C, Brown R S

机构信息

Harvard Medical School, Boston, MA 02115, USA.

出版信息

Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2938-43. doi: 10.1073/pnas.95.6.2938.

DOI:10.1073/pnas.95.6.2938
PMID:9501194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC19673/
Abstract

The crystal structure of the six NH2-terminal zinc fingers of Xenopus laevis transcription factor IIIA (TFIIIA) bound with 31 bp of the 5S rRNA gene promoter has been determined at 3.1 A resolution. Individual zinc fingers are positioned differently in the major groove and across the minor groove of DNA to span the entire length of the duplex. These results show how TFIIIA can recognize several separated DNA sequences by using fewer fingers than necessary for continuous winding in the major groove.

摘要

非洲爪蟾转录因子IIIA（TFIIIA）的六个氨基末端锌指与5S rRNA基因启动子的31个碱基对结合的晶体结构已在3.1埃分辨率下确定。各个锌指在DNA的大沟和小沟中的定位不同，以跨越双链体的整个长度。这些结果表明了TFIIIA如何通过使用比在大沟中连续缠绕所需的手指更少的手指来识别几个分开的DNA序列。