The immunophilin FKBP4 (FKBP52/FKBP59) maps to the distal short arm of human chromosome 12.

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作者信息

Bermingham N A, Rauf S, Katsanis N, Martin J E, Hunter A J, Fisher E M

机构信息

Neurogenetics Unit, Imperial College School of Medicine at St. Mary's, London, UK.

出版信息

Mamm Genome. 1998 Mar;9(3):268. doi: 10.1007/s003359900746.

DOI:10.1007/s003359900746

PMID:9501323

Abstract

摘要

相似文献

The immunophilin FKBP4 (FKBP52/FKBP59) maps to the distal short arm of human chromosome 12.

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The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain.亲免蛋白FKBP59-HBI与90kDa热休克蛋白相互作用的能力由其四肽重复结构域编码。

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Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes.人FKBP52的表达与特性研究，FKBP52是一种与90 kDa热休克蛋白相关的亲免素，也是类固醇受体复合物的一个组成部分。

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Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor.人FKBP51的分子克隆及免疫亲和素与Hsp90和孕激素受体相互作用的比较。

Mol Cell Biol. 1997 Feb;17(2):594-603. doi: 10.1128/MCB.17.2.594.

Stage-specific expression of the immunophilin FKBP59 messenger ribonucleic acid and protein during differentiation of male germ cells in rabbits and rats.免疫亲和素FKBP59信使核糖核酸和蛋白质在兔和大鼠雄性生殖细胞分化过程中的阶段特异性表达。

Biol Reprod. 1998 Feb;58(2):353-60. doi: 10.1095/biolreprod58.2.353.

P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors.P59（FK506结合蛋白59）与热休克蛋白的相互作用高度保守，可能涉及类固醇受体以外的蛋白质。

Biochemistry. 1993 Aug 31;32(34):8842-7. doi: 10.1021/bi00085a015.

Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65).一种新型65千道尔顿FK506结合蛋白（FKBP65）的分子克隆、DNA序列分析及生化特性研究

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FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin.FAP48是一种新蛋白，它能与免疫亲和素FKBP59和FKBP12形成特定复合物。免疫抑制剂FK506和雷帕霉素可起到预防作用。

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A breakpoint map of recurrent chromosomal rearrangements in human neoplasia.人类肿瘤中复发性染色体重排的断点图谱。

Nat Genet. 1997 Apr;15 Spec No:417-74. doi: 10.1038/ng0497supp-417.

Chaperone function of Hsp90-associated proteins.Hsp90相关蛋白的伴侣功能。

Science. 1996 Dec 6;274(5293):1715-7. doi: 10.1126/science.274.5293.1715.

A radiation hybrid map of the human genome.人类基因组的辐射杂种图谱。

Hum Mol Genet. 1996 Mar;5(3):339-46. doi: 10.1093/hmg/5.3.339.

A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains.一种由亲免素和其他通过四肽重复结构域与hsp90结合的蛋白质介导的蛋白质靶向模型。

J Biol Chem. 1996 Jun 7;271(23):13468-75. doi: 10.1074/jbc.271.23.13468.

Mapping the gene that encodes phosphatidylinositol-specific phospholipase C-gamma 2 in the human and the mouse.绘制人类和小鼠中编码磷脂酰肌醇特异性磷脂酶C-γ2的基因图谱。

Genomics. 1994 Sep 15;23(2):504-7. doi: 10.1006/geno.1994.1533.

Immunophilins and the nervous system.

Nat Med. 1995 Jan;1(1):32-7. doi: 10.1038/nm0195-32.

Chromosomal assignment and linkage analysis of the human glutathione S-transferase mu gene (GSTM1) using intron specific polymerase chain reaction.利用内含子特异性聚合酶链反应对人类谷胱甘肽S-转移酶μ基因（GSTM1）进行染色体定位和连锁分析。

Hum Genet. 1992 Dec;90(4):435-9. doi: 10.1007/BF00220473.

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