Obrand D I, Gordon P H
Department of Surgery, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Br J Surg. 1998 Feb;85(2):246-8. doi: 10.1046/j.1365-2168.1998.00507.x.
The aim of this study was to determine whether the previously reported shift in carcinoma from the left colon to the right colon has progressed.
The charts of 2169 patients admitted to one institution between 1979 and 1994 with a diagnosis of colorectal carcinoma were reviewed retrospectively. The study was divided into four equal intervals. The large bowel was divided into five regions: right, transverse, left, sigmoid and rectum.
Right-sided lesions increased from 20.6 to 29.9 per cent (P = 0.001) and rectal lesions decreased from 22.0 to 11.3 per cent (P = 0.0002) from the first to the fourth study interval. The frequency of transverse, left and sigmoid colon lesions remained relatively constant.
The continuing trend of increased incidence of right-sided lesions and decreased incidence of rectal lesions was documented. Any screening examination for carcinoma requires total examination of the colon.
本研究的目的是确定先前报道的结肠癌从左半结肠向右半结肠转移的情况是否仍在发展。
回顾性分析了1979年至1994年间一所机构收治的2169例诊断为结直肠癌患者的病历。研究分为四个相等的时间段。大肠分为五个区域：右半结肠、横结肠、左半结肠、乙状结肠和直肠。
从第一个研究时间段到第四个研究时间段，右侧病变从20.6%增加到29.9%（P = 0.001），直肠病变从22.0%下降到11.3%（P = 0.0002）。横结肠、左半结肠和乙状结肠病变的频率保持相对稳定。
记录了右侧病变发病率持续上升和直肠病变发病率持续下降的趋势。任何癌症筛查检查都需要对结肠进行全面检查。
