Secrétan M, Sickenberg M, Zografos L, Piguet B
Jules Gonin Hospital, University of Lausanne, Switzerland.
Retina. 1998;18(1):62-6. doi: 10.1097/00006982-199801000-00011.
To define the morphometric characteristics of indirect choroidal ruptures associated with choroidal neovascularization (CNV).
A total of 79 eyes that had sustained traumatic indirect choroidal ruptures was studied retrospectively. Color pictures of the fundus and fluorescein angiograms were available in all cases, and patients were followed for at least 1 year. Eyes that were free of CNV constituted Group I; eyes that developed CNV constituted Group II. Baseline characteristics of both groups, including age, sex, and visual acuity, were recorded. Distance of indirect choroidal ruptures from the center of the fovea and morphometric characteristics of the ruptures were calculated using image analysis software (Image 1.60; National Institutes of Health, Bethesda, MD).
A total of 63 eyes (79.7%) free of CNV was included in Group I and 16 eyes (20.3%) that developed CNV were included in Group II. Morphometric analysis showed a greater distance between the indirect choroidal rupture and the center of the fovea in Group I than in Group II (median, 1480 microm versus 612 microm; P = 0.009). In addition, the length of the rupture was shorter in Group I than in Group II (median, 3054 microm versus 4504 microm; P = 0.03).
Two significant factors associated with the presence of CNV in case of traumatic choroidal rupture were identified and quantified: the proximity of the rupture to the center of the fovea and the length of the rupture. Both should be considered as risk factors for the development of CNV and monitoring should take them into account.
明确与脉络膜新生血管（CNV）相关的间接性脉络膜破裂的形态学特征。
对79只发生外伤性间接性脉络膜破裂的眼睛进行回顾性研究。所有病例均有眼底彩色照片和荧光素血管造影，患者随访至少1年。无CNV的眼睛为I组；发生CNV的眼睛为II组。记录两组的基线特征，包括年龄、性别和视力。使用图像分析软件（Image 1.60；美国国立卫生研究院，马里兰州贝塞斯达）计算间接性脉络膜破裂距黄斑中心的距离以及破裂的形态学特征。
I组包括63只（79.7%）无CNV的眼睛，II组包括16只（20.3%）发生CNV的眼睛。形态学分析显示，I组中间接性脉络膜破裂与黄斑中心的距离大于II组（中位数，1480微米对612微米；P = 0.009）。此外，I组中破裂的长度短于II组（中位数，3054微米对4504微米；P = 0.03）。
确定并量化了外伤性脉络膜破裂时与CNV存在相关的两个重要因素：破裂与黄斑中心的接近程度以及破裂的长度。两者均应被视为CNV发生的危险因素，监测时应予以考虑。
