Maeda Y, Oyama H, Yoshimura K, Maeda H, Izutani T, Yamauchi T, Fukui I
Department of Urology, Cancer Institute Hospital.
Hinyokika Kiyo. 1998 Jan;44(1):33-5.
A 45-year-old house-wife, who had undergone surgical treatment for lung adenocarcinoma 2 years previously, presented with a left renal mass detected by follow-up CT. During 7 months of observation, it rapidly enlarged from 1 cm to 3 cm in maximum diameter. Although the short doubling time (40 days) suggested that the tumor was metastatic, abdominal urtrasonography, angiography and CT scan did not exclude primary renal cell carcinoma. Left nephrectomy was performed. Histologically, the tumor proved to be metastasis from the previous lung adenocarcinoma. She has been alive with pulmonary recurrence 13 months after nephrectomy. The doubling time of the tumor may be one of the key factors in differentiating a metastatic renal tumor from a primary carcinoma.
一位45岁的家庭主妇，两年前因肺腺癌接受了手术治疗，随访CT检查发现左肾有肿块。在7个月的观察期内，其最大直径从1厘米迅速增大至3厘米。尽管短倍增时间（40天）提示肿瘤为转移性，但腹部超声、血管造影和CT扫描均不能排除原发性肾细胞癌。遂行左肾切除术。组织学检查证实该肿瘤为先前肺腺癌的转移灶。肾切除术后13个月，她因肺部复发仍存活。肿瘤的倍增时间可能是鉴别转移性肾肿瘤与原发性癌的关键因素之一。
