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青少年类风湿关节炎患者葡萄膜炎的筛查

Screening for uveitis in juvenile rheumatoid arthritis.

作者信息

Boone M I, Moore T L, Cruz O A

机构信息

St. Louis Eye Institute, Mo., USA.

出版信息

J Pediatr Ophthalmol Strabismus. 1998 Jan-Feb;35(1):41-3. doi: 10.3928/0191-3913-19980101-13.

Abstract

BACKGROUND

Uveitis associated with juvenile rheumatoid arthritis (JRA) is an important cause of visual impairment in children. Because uveitis is often asymptomatic in this age group, frequent ophthalmologic screening examinations are recommended. Recent reports have found a decrease in the prevalence and severity of uveitis in JRA when compared to older data.

METHODS

The charts of 52 consecutive patients with JRA seen over a 30-month period were retrospectively reviewed.

RESULTS

Eye examination identified uveitis in five (12%) patients. All patients with uveitis were female, ANA positive, and had pauciarticular-onset arthritis. Three patients had the onset of uveitis before the age of 2. All patients have maintained good visual acuity and have not developed serious sight-threatening ocular complications over the follow-up period.

CONCLUSIONS

Although the prevalence and severity of JRA-associated uveitis may be decreasing, we strongly recommend continued strict adherence to the current screening guidelines.

摘要

背景

与青少年类风湿性关节炎(JRA)相关的葡萄膜炎是儿童视力损害的重要原因。由于葡萄膜炎在该年龄组中通常无症状,因此建议进行频繁的眼科筛查检查。最近的报告发现,与旧数据相比,JRA中葡萄膜炎的患病率和严重程度有所下降。

方法

回顾性分析了在30个月期间连续就诊的52例JRA患者的病历。

结果

眼部检查发现5例(12%)患者患有葡萄膜炎。所有葡萄膜炎患者均为女性,抗核抗体阳性,且患少关节起病性关节炎。3例患者在2岁之前出现葡萄膜炎。在随访期间,所有患者的视力均保持良好,未出现严重威胁视力的眼部并发症。

结论

尽管JRA相关葡萄膜炎的患病率和严重程度可能在下降,但我们强烈建议继续严格遵守当前的筛查指南。

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