Ahn J, Pogrel M A
School of Dentistry, University of California, San Francisco, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Feb;85(2):197-202. doi: 10.1016/s1079-2104(98)90426-7.
The dental pulp is a low-compliance system that is particularly vulnerable to physiologic changes. Prolonged vasoconstriction may have detrimental effects. This goal of this study was to determine whether 2% lidocaine with 1:100,000 epinephrine, as used for buccal infiltration, decreases the blood flow in the dental pulp and adjacent gingival tissue.
The Periflux PF3 laser Doppler monitored pulpal and gingival blood flow before and after injection with local anesthetic. Ten human volunteers with at least one healthy and unrestored maxillary premolar were used in this study.
After injection of 0.9 ml of 2% lidocaine with epinephrine, there was a significant reduction from baseline values (p > 0.05) in both pulpal (73%) and gingival (51%) blood flow rate in all volunteers. Blood flow had not returned to baseline values after 1 hour.
This study showed that 2% lidocaine with 1:100,000 epinephrine significantly reduced blood flow pulpally and gingivally. Pulpal blood flow reduction was more than gingival blood flow reduction, which may be critical for compromised pulps with already reduced blood flow. The gingival effects may be of relevance with soft tissue procedures.
牙髓是一个顺应性低的系统，特别容易受到生理变化的影响。长时间的血管收缩可能会产生有害影响。本研究的目的是确定用于颊侧浸润的含1:100,000肾上腺素的2%利多卡因是否会降低牙髓和相邻牙龈组织的血流。
使用Periflux PF3激光多普勒监测局部麻醉剂注射前后的牙髓和牙龈血流。本研究使用了10名至少有一颗健康且未修复的上颌前磨牙的人类志愿者。
在注射0.9毫升含肾上腺素的2%利多卡因后，所有志愿者的牙髓血流率（73%）和牙龈血流率（51%）均较基线值显著降低（p>0.05）。1小时后血流未恢复到基线值。
本研究表明，含1:100,000肾上腺素的2%利多卡因可显著降低牙髓和牙龈的血流。牙髓血流减少比牙龈血流减少更明显，这对于血流已经减少的受损牙髓可能至关重要。牙龈效应可能与软组织手术有关。
