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[一例特发性嗜酸性粒细胞增多综合征,特别涉及精神障碍和脑部影像]

[A case of idiopathic hypereosinophilic syndrome with special reference to mental disorders and brain images].

作者信息

Kataoka H, Konishi T, Nagano T, Suzumura A, Takayanagi T

机构信息

Department of Neurology, Kishiwada City Hospital.

出版信息

Rinsho Shinkeigaku. 1997 Nov;37(11):996-1000.

PMID:9503970
Abstract

We reported a case of idiopathic hypereosinophilic syndrome with psychiatric symptoms and abnormal areas in subcortical white matter on brain MRI. The 25-year-old man was referred to us because of fever, confusional state and emotional incontinence. He soon became apathetic and emotionless. While he was confused, we studied brain CT twice and brain MRI four times. In deep white matter around the lateral ventricles and the cortices of parietal lobe, occipital lobe and cerebellar hemispheres, T1-weighted MRI revealed low intensity areas and T2-weighted MRI showed high intensity areas. After gadolinium infusion, some above-stated areas were enhanced. The lesions in the deep white matter disappeared when symptoms diminished, while lesions in the occipital cortex remained unchanged. Brain MRI studies were beneficial and useful to analyse the rare idiopathic hypereosinophilic syndrome with psychic disorders.

摘要

我们报告了一例伴有精神症状且脑MRI显示皮质下白质有异常区域的特发性嗜酸性粒细胞增多综合征病例。该25岁男性因发热、意识模糊状态和情感失禁被转诊至我们科室。他很快变得冷漠且毫无情感。在他意识模糊期间,我们对其进行了两次脑部CT检查和四次脑部MRI检查。在侧脑室周围的深部白质以及顶叶、枕叶和小脑半球的皮质中,T1加权MRI显示低信号区,T2加权MRI显示高信号区。注入钆后,上述一些区域有强化表现。当症状减轻时,深部白质中的病变消失,而枕叶皮质中的病变保持不变。脑部MRI研究对于分析这种罕见的伴有精神障碍的特发性嗜酸性粒细胞增多综合征是有益且有用的。

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