Mishra Y, Mehta Y, Kohli V M, Kohli V, Mairal M, Mishra A, Bapna R K, Trehan N
Department of Cardiac Surgery and Anesthesiology Escorts Heart Institute and Research Centre, New Delhi.
Indian Heart J. 1997 Sep-Oct;49(5):511-7.
From March 1994 to April 1997, 433 patients had undergone coronary artery bypass grafting without cardiopulmonary bypass in our institute. Sixty-eight patients had various organ dysfunctions and/or aortic atheroma or calcification and were regarded as high risk for cardiopulmonary bypass. In 277 patients surgery was performed through midline sternotomy, while in 156 minithoracotomy approach was used. In 361 patients single coronary artery bypass grafting was done, and in 72 two-coronary arteries were bypassed. In 63 patients who had graftable vessels in anterior wall and diffusely diseased ungraftable vessels in posterolateral and/or inferior wall, transmyocardial laser revascularisation was also done along with coronary artery bypass grafting to achieve complete myocardial revascularisation. Nine patients in this series were also subjected to simultaneous carotid endarterectomy along with myocardial revascularisation. In two patients complementary percutaneous transluminal coronary angioplasty of left circumflex coronary artery was done five days after minithoracotomy and left internal mammary artery to left anterior descending coronary artery bypass grafting. Forty-two cases were extubated in operating room. Average blood loss was 260 ml. Six patients were reexplored for postoperative bleeding. Seven patients had perioperative myocardial infarction. One developed neurological complication. Hospital mortality was 2.3 percent (10/433 cases) and four deaths were due to malignant ventricular arrhythmias. Nine patients developed chest wound complications. Average hospital stay after operation was six days, 423 patients were discharged from hospital and all of them were asymptomatic. During three years follow-up (range 3 to 38 months) there were three known cardiac deaths. Ninety percent (391) patients reported to the follow-up clinic and 91 percent of them were angina-free. In patients who were subjected to transmyocardial laser revascularisation along with coronary artery bypass grafting, myocardial perfusion scan showed a step-wise improvement in reversible ischemia. The perfusion index increased from 52 percent at three months to 90 percent at 12 months. We conclude that coronary artery bypass grafting without cardiopulmonary bypass can be done with relatively low mortality, more so in a group of patients in whom cardiopulmonary bypass poses a high risk. Transmyocardial laser revascularisation is a suitable means to provide complete myocardial revascularisation along with coronary artery bypass surgery in patients who have graftable vessels in anterior wall and ungraftable vessels in posterolateral and inferior walls.
1994年3月至1997年4月,我院433例患者接受了非体外循环冠状动脉搭桥术。68例患者存在各种器官功能障碍和/或主动脉粥样硬化或钙化,被视为体外循环的高危患者。277例患者通过正中胸骨切开术进行手术,156例采用微创胸廓切开术。361例患者进行了单支冠状动脉搭桥术,72例进行了双支冠状动脉搭桥术。63例患者前壁有可搭桥血管,后外侧和/或下壁有弥漫性病变不可搭桥血管,在冠状动脉搭桥术的同时还进行了经心肌激光血运重建术,以实现完全心肌血运重建。本系列中有9例患者在心肌血运重建的同时还接受了同期颈动脉内膜切除术。2例患者在微创胸廓切开术及左乳内动脉至左前降支冠状动脉搭桥术后5天,对左旋支冠状动脉进行了补充经皮冠状动脉腔内血管成形术。42例患者在手术室拔管。平均失血量为260毫升。6例患者因术后出血再次手术。7例患者发生围手术期心肌梗死。1例发生神经系统并发症。医院死亡率为2.3%(10/433例),4例死亡归因于恶性室性心律失常。9例患者发生胸部伤口并发症。术后平均住院时间为6天,423例患者出院,均无症状。在三年随访期间(范围为3至38个月),有3例已知的心脏死亡病例。90%(391例)的患者到随访门诊复诊,其中91%无心绞痛症状。在接受经心肌激光血运重建术及冠状动脉搭桥术的患者中,心肌灌注扫描显示可逆性缺血呈逐步改善。灌注指数从3个月时的52%增加到12个月时的90%。我们得出结论,非体外循环冠状动脉搭桥术可以在相对较低的死亡率下完成,在体外循环风险较高的一组患者中更是如此。经心肌激光血运重建术是为前壁有可搭桥血管而后外侧和下壁有不可搭桥血管的患者在冠状动脉搭桥手术的同时提供完全心肌血运重建的合适方法。