Hidai H, Chiba T, Takagi Y, Mori T, Taniguchi T, Hyodo T
Department of Urology, Yokohama Dai-ichi Hospital, Japan.
Surg Today. 1998;28(1):114-6. doi: 10.1007/BF02483623.
We developed a simple and easy nonsurgical percutaneous method for autografting parathyroid tissue into the forearm muscles. This method was applied to 30 patients suffering from secondary hyperparathyroidism who were then refractory to medical treatment. The operative results were then compared with 16 patients who underwent treatment using Wells' method. The graft "take," judged by a significant intact parathyroid hormone (PTH) ratio (> 1.5) between grafted and nongrafted arm vein blood, was 82% for the percutaneous method group and 75% for the Wells' method group, respectively. The percentage of recurrent hyperparathyroidism necessitating a subtotal removal of the autograft was equal in the two groups. No complications were noted for either method. Wells' method can thus be replaced by this simple and easy nonoperative method.
我们开发了一种简单易行的非手术经皮方法,用于将甲状旁腺组织自体移植到前臂肌肉中。该方法应用于30例药物治疗无效的继发性甲状旁腺功能亢进患者。然后将手术结果与16例采用韦尔斯方法治疗的患者进行比较。通过移植侧与未移植侧手臂静脉血中完整甲状旁腺激素(PTH)比值显著升高(>1.5)来判断移植“成功”,经皮方法组为82%,韦尔斯方法组为75%。两组中因复发性甲状旁腺功能亢进而需要对自体移植组织进行次全切除的百分比相同。两种方法均未发现并发症。因此,韦尔斯方法可以被这种简单易行的非手术方法所取代。