Gorshkov A N, Komissarchik Ia Iu
Institute of Cytology, Russian Academy of Sciences, St. Petersburg.
Tsitologiia. 1997;39(11):1032-7.
The structural reorganization of actin cytoskeleton of the frog urinary bladder granular cells, in the process of vasopressin-induced water transport, was studied by fluorescent and electron microscopy, and immunocytochemistry. A significant decrease in density of actin microfilament network under the apical membrane was observed after water transport stimulation. Microfilaments were associated with membranes of large vacuoles emerging in granular cells of vasopressin-treated urinary bladders. A supposition is advanced concerning functional heterogeneity of actin filaments in granular cells.
通过荧光显微镜、电子显微镜和免疫细胞化学技术,研究了蛙膀胱颗粒细胞在血管加压素诱导水转运过程中肌动蛋白细胞骨架的结构重组。水转运刺激后,观察到顶端膜下肌动蛋白微丝网络密度显著降低。微丝与血管加压素处理的膀胱颗粒细胞中出现的大液泡膜相关。提出了关于颗粒细胞中肌动蛋白丝功能异质性的假设。