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[慢性脑缺血综合治疗体系中的脑脊液吸附作用]

[Cerebrospinal fluid sorption in the system of complex treatment of chronic cerebral ischemia].

作者信息

Shulëv Iu A, Starchenko A A, Bikmullin V N, Dorosh K V, Martynov B V

出版信息

Vestn Khir Im I I Grek. 1997;156(6):45-8.

PMID:9505387
Abstract

The cerebrospinal fluid was investigated in 16 patients with chronic cerebral ischemia. Reactions of the local immune system of the liquor was shown to change by the autoimmune type. Medical efficiency of cerebrospinal fluid sorption was proved and it can be considered a method of detoxication aimed at breaking the pathogenetic chain: formation of abundance of the autoantibodies--increased amount of the circulating immunocomplexes--damage of the cell membranes--discharge of deep antigens--appearance of a new generation of autoantibodies. Using cerebrospinal fluid sorption as a test for the detection of latent functional reserves of the neurons not changed irreversibly in the zone of reduced perfusion of the cerebral tissue is thought to be a perspective method.

摘要

对16例慢性脑缺血患者的脑脊液进行了研究。结果显示,脑脊液局部免疫系统的反应呈自身免疫类型改变。证实了脑脊液吸附的医疗效果,可将其视为一种旨在打破致病链的解毒方法:自身抗体大量形成——循环免疫复合物数量增加——细胞膜损伤——深部抗原释放——新一代自身抗体出现。将脑脊液吸附作为检测脑组织灌注减少区域未发生不可逆改变的神经元潜在功能储备的一种试验,被认为是一种有前景的方法。

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