氟他胺光敏反应——残留白癜风皮损
Flutamide photosensitivity--residual vitiliginous lesions.
作者信息
Vilaplana J, Romaguera C, Azón A, Lecha M
机构信息
Servei de Dermatologia, Hospital Clínic i Provincial, Facultat de Medicina, Universitat de Barcelona, Spain.
出版信息
Contact Dermatitis. 1998 Feb;38(2):68-70. doi: 10.1111/j.1600-0536.1998.tb05655.x.
A case of flutamide photosensitivity is reported in a patient receiving treatment for prostate cancer. Photopatch testing with flutamide at 10 and 20% in acetone was positive and controls negative. Other reports in the literature indicate that flutamide photosensitivity can be produced either by UV-A or UV-B, but the small number of reports and the differences in the tests performed do not allow the specific characteristics of flutamide photosensitivity to be established. Presently it would be advisable, due to the frequent use of this drug, to include flutamide in the investigation of photosensitive patients.
本文报道了1例接受前列腺癌治疗的患者出现氟他胺光敏反应的病例。用10%和20%的氟他胺丙酮溶液进行光斑贴试验呈阳性，而对照试验为阴性。文献中的其他报道表明，氟他胺光敏反应可由紫外线A或紫外线B诱发，但报道数量较少且所进行的试验存在差异，因此无法确定氟他胺光敏反应的具体特征。鉴于该药物使用频繁，目前建议在对光敏患者的调查中纳入氟他胺。
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