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住院老年充血性心力衰竭患者的抑郁情况

Depression in hospitalized older patients with congestive heart failure.

作者信息

Koenig H G

机构信息

Duke University Medical Center, Durham, NC 27710, USA.

出版信息

Gen Hosp Psychiatry. 1998 Jan;20(1):29-43. doi: 10.1016/s0163-8343(98)80001-7.

Abstract

The objectives of this study were to examine the prevalence of depression in hospitalized, medically ill, older patients with and without congestive heart failure (CHF), and examine correlates, course, predictors of outcome, and treatment of depression in patients with CHF. A consecutive sample of 542 patients age 60 or over admitted to inpatient services of Duke University Medical Center were systematically screened by a psychiatrist for depression using the Diagnostic Interview Schedule; 342 depressed cases and nondepressed controls were identified. Of these, 107 had a primary or secondary diagnosis of CHF. Among patients with CHF, major depression was identified in 36.5%, a rate that was significantly higher than for patients without CHF (25.5%); the difference was largely explained by low rates of major depression in cardiac patients without CHF (17.0%) who had less severe physical illness. Minor depression was also present in 21.5% of CHF patients, but was not more prevalent than in patients without CHF (17.0%). Compared with nondepressed CHF patients, those with depression were more likely to have comorbid psychiatric disorder, severe medical illness, and severe functional impairment. Depressed patients used more outpatient and inpatients medical services, although this was largely due to the severity of their health problems. Patients often remained depressed for a prolonged period, and over 40% failed to remit during the year following discharge. Factors predicting slower remission included nonhealth-related, stressful life events and low social support; physical health factors at baseline had little effect. The majority of depressed CHF patients did not receive treatment for their depression with either antidepressants or psychotherapy, and did not see mental health specialists any more frequently than did the nondepressed. These findings are of concern and have important implications for the diagnosis and treatment of depression in older patients with heart failure.

摘要

本研究的目的是调查住院的患有和未患有充血性心力衰竭(CHF)的老年内科疾病患者中抑郁症的患病率,并研究CHF患者抑郁症的相关因素、病程、预后预测因素及治疗情况。杜克大学医学中心住院部连续纳入了542名60岁及以上的患者,由精神科医生使用诊断访谈表对其进行抑郁症系统筛查;共识别出342例抑郁症患者和非抑郁症对照。其中,107例有CHF的一级或二级诊断。在CHF患者中,重度抑郁症的识别率为36.5%,显著高于无CHF患者(25.5%);这种差异主要是由于无CHF的心脏病患者中重度抑郁症发生率较低(17.0%),这些患者身体疾病较轻。21.5%的CHF患者也存在轻度抑郁症,但并不比无CHF患者更普遍(17.0%)。与非抑郁症CHF患者相比,抑郁症患者更可能合并精神疾病、患有严重内科疾病和存在严重功能障碍。抑郁症患者使用了更多的门诊和住院医疗服务,不过这在很大程度上是由于他们健康问题的严重性。患者的抑郁状态往往会持续很长时间,超过40%的患者在出院后的一年内未能缓解。预测缓解较慢的因素包括与健康无关的应激性生活事件和低社会支持;基线时的身体健康因素影响不大。大多数抑郁症CHF患者未接受抗抑郁药或心理治疗,看精神科专科医生的频率也不比非抑郁症患者更高。这些发现令人担忧,对老年心力衰竭患者抑郁症的诊断和治疗具有重要意义。

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