Benzodipyran derivatives with antiallergic activity.
作者信息
Bantick J R, Cairns H, Chambers A, Hazard R, King J, Lee T B
出版信息
J Med Chem. 1976 Jun;19(6):817-21. doi: 10.1021/jm00228a016.
PMID:950652
Abstract
The synthesis and antiallergic activity of a number of benzodipyrandicarboxylic acids are described. Antiallergic activity of the compounds was determined using the homologous passive cutaneous anaphylaxis (PCA) reaction in the rat. The structural requirements for activity in the PCA screen are discussed. In this test system the linear benzodipyrans are more active than their angular analogues.
摘要
Zotero 插件