Lin W Y, Lan J L, Cheng K Y, Wang S J
Department of Nuclear Medicine, Taichung Veterans General Hospital, Chung-Tai College of Medical Technology, Taiwan, ROC.
Scand J Rheumatol. 1998;27(1):42-5. doi: 10.1080/030097498441164.
In this study, we evaluated the relationship between the gallium uptake in the kidneys and the results of renal biopsy. The renal uptake of gallium in 32 patients with lupus nephritis were evaluated according to the classification of the World Health Organization, the activity index (AI), and the chronicity index (CI). AI was significantly higher in patients with a positive gallium scan when compared with patients with a negative gallium scan (p = 0.0007). However, change in gallium uptake was not related to the CI or WHO classification (p = 0.68 and p = 0.79 respectively). Of the 16 patients with AI > or = 9, 13 (81.25%) had a positive gallium scan, while only 3 (18.7%) of the patients with AI < 9 had a positive scan. In addition, all patients (100%) with AI > or = 11 showed a positive gallium scan. We conclude that renal imaging with gallium has a good correlation with AI, and may be a useful alternative to renal biopsy in patients with lupus nephritis.
在本研究中，我们评估了肾脏镓摄取与肾活检结果之间的关系。根据世界卫生组织的分类、活动指数（AI）和慢性指数（CI），对32例狼疮性肾炎患者的肾脏镓摄取情况进行了评估。镓扫描阳性的患者AI显著高于镓扫描阴性的患者（p = 0.0007）。然而，镓摄取的变化与CI或世界卫生组织分类无关（分别为p = 0.68和p = 0.79）。在16例AI≥9的患者中，13例（81.25%）镓扫描阳性，而AI＜9的患者中只有3例（18.7%）扫描阳性。此外，所有AI≥11的患者（100%）镓扫描均为阳性。我们得出结论，肾脏镓显像与AI具有良好的相关性，对于狼疮性肾炎患者可能是肾活检的一种有用替代方法。
