Erina E V, Labeeva T N, Pershakova L P
Kardiologiia. 1976 May;16(5):18-25.
The paper analyses the results of a study of the clinical peculiarities of the course of essential hypertension with crises, of the changes in the functional state of the central nervous system, and of some neuro-humoral systems of the human body. In most of the patients tending to develope frequent crises distinct changes were noted in the EEG that indicate dysfunction of the hypothalamic zone and of the reticular formation of the brain stem, their clinical course being characterized by significant astheno-neurotic disorders with autonomous dysfunction and cerebral angiodistonic disturbances. For the prevention of crises it is essential to conduct a pathogenetically substantiated and highly differentiated systematic therapy, as well as special measures aimed at increasing the endurance of the central nervous system, improving the circulation and metabolic processes in the brain, decreasing tnd hypothalamic structures of the brain, and correcting the dishormonal disorders.
本文分析了一项关于伴有危象的原发性高血压病程的临床特点、中枢神经系统功能状态变化以及人体某些神经 - 体液系统变化的研究结果。在大多数倾向于频繁发生危象的患者中，脑电图显示出明显变化，这表明下丘脑区和脑干网状结构功能障碍，其临床病程的特征是伴有自主神经功能障碍和脑血管张力障碍的显著虚弱 - 神经症性障碍。为预防危象，必须进行基于发病机制的、高度个体化的系统治疗，以及采取旨在增强中枢神经系统耐力、改善脑循环和代谢过程、减少脑下丘脑结构负担和纠正激素紊乱的特殊措施。
