Hanano R, Kaufmann S H
Dept of Immunology, University of Ulm, Germany. ralph.hanano@medizin,uni-ulm.de
Trends Microbiol. 1998 Feb;6(2):71-5. doi: 10.1016/S0966-842X(97)01204-3.
Pneumocystis carinii causes serious disease in immunocompromised patients, notably in AIDS patients. Our understanding of the biology of this fungus is advancing but still incomplete. Protective immunity against P. carinii is mediated by CD4+ T cells in the immunocompetent host, but precise resistance mechanisms remain to be determined.
卡氏肺孢子菌可在免疫功能低下的患者中引发严重疾病，尤其是艾滋病患者。我们对这种真菌生物学特性的认识正在不断深入，但仍不完整。在免疫功能正常的宿主中，针对卡氏肺孢子菌的保护性免疫由CD4 + T细胞介导，但确切的抵抗机制仍有待确定。
