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[关于5例盘尾丝虫病水肿的新病例]

[Apropos of 5 new cases of onchocerciasis edema].

作者信息

Nozais J P, Caumes E, Datry A, Bricaire F, Danis M, Gentilini M

机构信息

Département des maladies infectieuses, parasitaires et tropicales et de santé publique, CHU Pitié-Salpétrière, Paris, France.

出版信息

Bull Soc Pathol Exot. 1997;90(5):335-8.

PMID:9507765
Abstract

We report 5 cases of onchocerciasis presenting as limb's swelling collected in the tropical disease unit of a parisian hospital between 1982 and 1993. They are 5 men which have lived between 3 weeks and 4 years in forested areas of Cameroon in four cases and Côte d'Ivoire in one case. The incubation period varied from 5 months to 2 years. The limb oedema was always located to one arm. It was associated with a blood eosinophilia above 2000/mm3 in 4 of 5 patients. The skin detection of microfilaria of Onchocerca volvulus was positive in every case. The serodiagnostic tests were negative for indirect immunoflurescent assay and immunoelectrophoresis with exception of one patient. These patients were cured with ivermectine and/or diethylcarbamazine. In addition, 26 other cases described in the literature are discussed.

摘要

我们报告了1982年至1993年间在巴黎一家医院的热带病科收治的5例表现为肢体肿胀的盘尾丝虫病病例。他们均为男性,其中4例在喀麦隆的森林地区生活了3周至4年,1例在科特迪瓦生活。潜伏期从5个月到2年不等。肢体水肿总是局限于一侧手臂。5例患者中有4例伴有血液嗜酸性粒细胞增多超过2000/mm³。每例患者皮肤检测盘尾丝虫微丝蚴均为阳性。除1例患者外,间接免疫荧光试验和免疫电泳的血清学诊断试验均为阴性。这些患者用伊维菌素和/或乙胺嗪治愈。此外,还讨论了文献中描述的其他26例病例。

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