Atzori C, Agostoni F, Angeli E, Cargnel A, Drago L, Gismondo M R
II Div. Inf. Dis., L. Sacco Hosp. Milan, Italy.
J Eukaryot Microbiol. 1997 Nov-Dec;44(6):30S. doi: 10.1111/j.1550-7408.1997.tb05754.x.
The development of in vitro experimental chemotherapy against P.carinii has been hindered by the lack of efficient methods for continuous cultivation of the microorganism. Various short-term systems, allowing the production of infectious forms of Pneumocystis, can be employed for in vitro experimental chemotherapy. The purpose of the present study is to describe a statistically relevant algorithmic model for the evaluation of P.carinii in short-term in vitro culture and drug screening.