Waszczuk J, Duława J, Kokot F, Bar A
Katedry i Kliniki Nefrologii Sl., Katowicach.
Pol Arch Med Wewn. 1997 Aug;98(8):111-6.
Studies were performed in 22 patients with diabetes mellitus type I, in 19 patients with diabetes type II, and in 15 healthy subjects. In all subjects the following parameters were assessed: creatinine clearance and 24 h urinary excretion of THP, albumin, sodium, potassium, and calcium. All studies were performed twice: first after 3 days on a normal sodium diet and subsequently after 3 days of sodium restriction (30-40 mmol Na/24 h). Urinary excretion of sodium was significantly lower in patients with diabetes mellitus type II than in healthy subjects. In patients with diabetes mellitus type I urinary excretion of sodium was significantly lower than in controls only after sodium restriction. No significant correlation was found between urinary excretion of THP and electrolytes. Results obtained in this study do not confirm presence of any relationship between urinary excretion THP and electrolytes.
对22名I型糖尿病患者、19名II型糖尿病患者和15名健康受试者进行了研究。对所有受试者评估了以下参数：肌酐清除率以及THP、白蛋白、钠、钾和钙的24小时尿排泄量。所有研究均进行两次：第一次在正常钠饮食3天后进行，随后在钠限制（30 - 40 mmol Na/24小时）3天后进行。II型糖尿病患者的尿钠排泄量显著低于健康受试者。I型糖尿病患者仅在钠限制后尿钠排泄量显著低于对照组。未发现THP尿排泄量与电解质之间存在显著相关性。本研究获得的结果未证实THP尿排泄量与电解质之间存在任何关系。
