[葡萄膜黑色素瘤患者中的白细胞介素-6]
[Interleukin-6 in patients with uveal melanoma].
作者信息
Likhvantseva V G, Slepova O S, Gerasimenko V A
机构信息
NII of Eye Diseases of Gel'mgol'ts, Moscow.
出版信息
Vestn Oftalmol. 1997 Sep-Oct;113(5):39-41.
PMID:9508749
Abstract
Studies of the blood serum and tears of patients with uveal melanoma revealed local (14.3%) and total-systems (11.1%) production of interleukin-6 (IL-6). Surgery stimulates IL-6 production in the serum (22.2%) and more so in tears (57.1%). The rate of IL-6 detection in the serum and the iridociliary localization of the tumor correlated with tumor development from stage T3 to stage T4. However, we failed to find out precisely the role of this cytokine.
摘要
对葡萄膜黑色素瘤患者的血清和泪液研究发现，白细胞介素-6（IL-6）存在局部（14.3%）和全身（11.1%）产生的情况。手术会刺激血清中IL-6的产生（22.2%），在泪液中刺激作用更强（57.1%）。血清中IL-6的检测率以及肿瘤的虹膜睫状体定位与肿瘤从T3期发展到T4期相关。然而，我们未能确切查明这种细胞因子的作用。
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