Anurova O A, Likhvantseva V G, Vereshchagina M V
Vestn Oftalmol. 2007 Sep-Oct;123(5):41-4.
The authors studied the expression of the protooncogen receptor involved in the regulation of major cell cycle processes in uveal melanoma. The studies performed by a highly sensitive immunohistochemical technique. The findings have allowed the authors to state that the membranous CD117/C-Kit receptor plays an important role in the progression of uveal melanomas. It is suggested that the use of the new drug Glivec is promising in treating uveal melanoma.
作者研究了参与葡萄膜黑色素瘤主要细胞周期进程调控的原癌基因受体的表达。这些研究采用了高度敏感的免疫组织化学技术。研究结果使作者得以指出,膜性CD117/C-Kit受体在葡萄膜黑色素瘤的进展中起重要作用。有人提出,使用新药格列卫治疗葡萄膜黑色素瘤具有前景。