Tasaki N, Okamoto M, Yamada T, Sueda T, Hashimoto M, Karakawa S, Ohishi Y
Department of Cardiology, Hiroshima Prefectural Hospital.
Intern Med. 1998 Jan;37(1):65-8. doi: 10.2169/internalmedicine.37.65.
We could detect recruitable backward collateral flow in systole and diastole by using a Doppler guide wire during coronary artery spasm in a 42-year-old female among 20 patients with documented variant angina. The electrocardiogram (ECG) showed no ST-segment deviation, although she had chest pain and her coronary angiography showed a totally occluded right coronary artery. After administration of isosorbide dinitrate (ISDN) the collateral flow disappeared and the flow pattern recovered to normal. The good collateral flow pattern in patient with totally occluded coronary artery due to spasm was indicated to relieve myocardial ischemia, even when the patient felt chest pain.
在20例确诊为变异型心绞痛的患者中,我们对一名42岁女性患者在冠状动脉痉挛期间使用多普勒导丝检测到了收缩期和舒张期可招募的逆向侧支血流。尽管她有胸痛症状且冠状动脉造影显示右冠状动脉完全闭塞,但心电图(ECG)未显示ST段偏移。给予硝酸异山梨酯(ISDN)后,侧支血流消失,血流模式恢复正常。结果表明,即使患者感到胸痛,因痉挛导致冠状动脉完全闭塞的患者中良好的侧支血流模式也能缓解心肌缺血。