Okano M
Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
Acta Paediatr. 1998 Jan;87(1):11-8. doi: 10.1080/08035259850157796.
Recent advances of the various laboratory tests to detect Epstein-Barr virus (EBV) infection have clarified the causative role for a spectrum of EBV-associated diseases. They include lymphoproliferative disorders (LPD), which occur in immunologically compromised individuals, Hodgkin's disease (HD), chronic active EBV infection (CAEBV), virus-associated hemophagocytic syndrome (VAHS), certain forms of T cell lymphoma, and some gastric carcinomas, in addition to the classical EBV-associated diseases such as EBV genome-positive Burkitt's lymphoma (BL), undifferentiated nasopharyngeal carcinoma (NPC) and infectious mononucleosis (IM). This review intends to introduce the recent progress of studies on EBV infection mainly from the clinical points of view.
检测爱泼斯坦-巴尔病毒（EBV）感染的各种实验室检测方法的最新进展，已阐明了EBV相关疾病谱的致病作用。这些疾病包括发生在免疫功能低下个体中的淋巴增殖性疾病（LPD）、霍奇金病（HD）、慢性活动性EBV感染（CAEBV）、病毒相关噬血细胞综合征（VAHS）、某些形式的T细胞淋巴瘤以及一些胃癌，此外还有经典的EBV相关疾病，如EBV基因组阳性的伯基特淋巴瘤（BL）、未分化鼻咽癌（NPC）和传染性单核细胞增多症（IM）。本综述旨在主要从临床角度介绍EBV感染研究的最新进展。
