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[血液吸附及联合治疗对重型颅脑创伤患者脑灌注压的影响]

[Effects of hemosorption and combined therapy on cerebral perfusion pressure in patients with severe craniocerebral trauma].

作者信息

Isaev Iu V, Dhangirova G M, Bichurina V A, Asriiants S Iu, Poliakh V F, Fedorova V Iu, Shadrin A G

出版信息

Anesteziol Reanimatol. 1997 Nov-Dec(6):46-7.

PMID:9511247
Abstract

Hemoperfusion with local heparin before and protamine after the column was used in the treatment of patients with grave craniocerebral injury. Effect of such treatment on the cerebral perfusion pressure (CPP) is analyzed. The treatment did not increase the liquor pressure but decreased it by 20-25 mm H2O in both groups of patients. CPP in the survivors improved and normalized. In the other group (dead patients) CPP did not change, despite a decrease of the liquor pressure, and remained high. These values can be prognostically important.

摘要

对重症颅脑损伤患者采用在柱前用局部肝素、柱后用鱼精蛋白进行血液灌流治疗。分析了该治疗对脑灌注压(CPP)的影响。治疗未使颅内压升高,两组患者的颅内压均降低了20 - 25 mmH₂O。存活患者的CPP得到改善并恢复正常。在另一组(死亡患者)中,尽管颅内压降低,但CPP没有变化,仍维持在较高水平。这些数值在预后方面可能具有重要意义。

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