头孢匹罗对产超广谱β-内酰胺酶肺炎克雷伯菌的疗效
[Effectiveness of cefpirome on Klebsiella pneumoniae producing beta-lactamases with an extended spectrum of activity].
作者信息
Kolár M
机构信息
Mikrobiologický ústav, Lékarská fakulta Univerzity Palackého, Olomouc.
出版信息
Epidemiol Mikrobiol Imunol. 1998 Feb;47(1):12-4.
PMID:9511280
Abstract
In the submitted paper the author investigated the effectiveness of cefpirome on Klebsiella pneumoniae strains producing beta-lactamases with an extended spectrum (ESBL). From a total of 1348 examined strains of Klebsiella pneumoniae ESBL production was confirmed in 59 strains (4.4%). Resistance of ESBL-positive strains of Klebsiella pneumoniae to ceftazidime was 83.1%, to cefotaxime 93.2%, while resistance to cefpirome was recorded only in 45.8%.
摘要
在提交的论文中，作者研究了头孢匹罗对产超广谱β-内酰胺酶（ESBL）的肺炎克雷伯菌菌株的有效性。在总共1348株检测的肺炎克雷伯菌菌株中，有59株（4.4%）被证实产ESBL。产ESBL的肺炎克雷伯菌菌株对头孢他啶的耐药率为83.1%，对头孢噻肟为93.2%，而对头孢匹罗的耐药率仅为45.8%。
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