Allard C, Mohandas N, Wacjman H, Krisnnamoorthy R
Nouv Rev Fr Hematol (1978). 1976 Jun;16(1):23-35.
The authors describe a new variant of unstable hemoglobin: hemoglobin Bicêtre, responsible for a severe hemolytic anemia in a young girl. This hemoglobin is characterized by the replacement of distal histidine (beta63 (E7)) by a proline, causing the molecule to be very unstable and very readily oxidized.
