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[A case of great instability of the hemoglobin: hemoglobin bicêtre (author's transl)].

作者信息

Allard C, Mohandas N, Wacjman H, Krisnnamoorthy R

出版信息

Nouv Rev Fr Hematol (1978). 1976 Jun;16(1):23-35.

PMID:951180
Abstract

The authors describe a new variant of unstable hemoglobin: hemoglobin Bicêtre, responsible for a severe hemolytic anemia in a young girl. This hemoglobin is characterized by the replacement of distal histidine (beta63 (E7)) by a proline, causing the molecule to be very unstable and very readily oxidized.

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