Reed J B, Morse L S, Schwab I R
Department of Ophthalmology, University of California, Davis, Sacramento 95816, USA.
Am J Ophthalmol. 1998 Mar;125(3):409-11. doi: 10.1016/s0002-9394(99)80163-9.
To report the response of acute Behçet retinitis to high-dose corticosteroids.
Case report. A 58-year-old man with Behçet disease and severe bilateral glaucoma experienced a sudden decrease of visual acuity to counting fingers in his (better-seeing) left eye. Examination disclosed hypopyon uveitis and an infiltrative retinitis threatening the fovea. He received intravenous methylprednisolone hemisuccinate, 1 gram per hour on each of 3 successive days, followed by oral prednisone and cyclosporine.
The retinal infiltrate disappeared within 24 hours. Visual acuity improved to LE, 20/400 by day 5 and returned to LE, 20/30 after 3 months. A visual field demonstrated a scotoma corresponding to the location of the previous retinitis.
High-dose intravenous methylprednisolone can reverse severe vision loss in acute Behçet retinitis.
报告大剂量皮质类固醇对急性白塞氏视网膜病变的疗效。
病例报告。一名58岁患有白塞氏病和严重双侧青光眼的男性，其（视力较好的）左眼视力突然降至只能数指。检查发现前房积脓性葡萄膜炎和累及黄斑的浸润性视网膜病变。他接受了静脉注射半琥珀酸甲泼尼龙，连续3天每天每小时1克，随后口服泼尼松和环孢素。
视网膜浸润在24小时内消失。视力在第5天提高到左眼20/400，3个月后恢复到左眼20/30。视野检查显示与先前视网膜病变部位相对应的暗点。
大剂量静脉注射甲泼尼龙可逆转急性白塞氏视网膜病变导致的严重视力丧失。
