von Zallinger C, Tempel K
Institut für Pharmakologie, Toxikologie und Pharmazie der Tierärztlichen Fakultät der Universität München.
Berl Munch Tierarztl Wochenschr. 1998 Feb;111(2):60-9.
A review of the latest literature concerning the present level of radiation therapy in veterinary medicine is given. In a general section physico-technical as well as biological fundamentals are discussed. In the special part of the paper indications for a radiation therapy of dogs, cats and horses are stated. In this respect the basis for a decision is the TNM-classification into different clinical stages according to the directions of the WHO. Tumors of the hemolymphatic system are very responsive to radiation therapy. While epithelial tumors are sensitive, tumors arising from the mesenchymal tissues react less sensitive. Melanoma and osteosarcoma seem to be resistant to radiation therapy. Besides this, radiation therapy is often questioned by the tolerance of the normal tissue.
本文对兽医学中放射治疗的当前水平的最新文献进行了综述。在一般部分中,讨论了物理技术以及生物学基础。在论文的特殊部分,阐述了犬、猫和马放射治疗的适应症。在这方面,决策的依据是根据世界卫生组织的指导方针将TNM分类为不同的临床阶段。血液淋巴系统的肿瘤对放射治疗非常敏感。上皮性肿瘤敏感,而间充质组织产生的肿瘤反应较不敏感。黑色素瘤和骨肉瘤似乎对放射治疗有抗性。除此之外,放射治疗经常受到正常组织耐受性的质疑。