Violanti J M, Vena J E, Petralia S
Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo 14214, USA.
Am J Ind Med. 1998 Apr;33(4):366-73. doi: 10.1002/(sici)1097-0274(199804)33:4<366::aid-ajim6>3.0.co;2-s.
This study presents findings from an updated retrospective cohort mortality study of male police officers from January 1, 1950 to December 31, 1990 (n = 2,593; 58,474 person-years; 98% follow-up). Significantly higher than expected mortality rates were found for all cause mortality (Standardized mortality ratio [SMR] = 110; 95% confidence interval [95% CI] = 1.04-1.17), all malignant neoplasms (SMR = 125; 95% CI = 1.10-1.41), cancer of the esophagus (SMR = 213; 95% CI = 1.01-3.91), cancer of the colon (SMR = 187; 95% CI = 1.29-2.59), cancer of the kidney (SMR = 2.08, 95% CI = 100-3.82), Hodgkin's disease (SMR = 313; 95% CI = 1.01-7.29), cirrhosis of the liver (SMR = 150; 95% CI = 1.00-2.16), and suicide (SMR = 153; 95% CI = 1.00-2.24). All accidents were significantly lower (SMR = 53; 95% CI = 0.34-0.79). Mortality by years of police service showed higher than expected rates for (1) all malignant neoplasms in the 1- to 9-years-of-service group; (2) all causes, bladder cancer, leukemia, and arteriosclerotic heart disease in the 10 to 19-year group; and (3) colon cancer and cirrhosis of the liver in the over 30 years of service group. Hypotheses for findings are discussed.
本研究展示了一项更新的回顾性队列死亡率研究的结果,该研究对象为1950年1月1日至1990年12月31日期间的男性警察(n = 2,593;58,474人年;随访率98%)。研究发现,全因死亡率(标准化死亡率[SMR]=110;95%置信区间[95%CI]=1.04 - 1.17)、所有恶性肿瘤(SMR = 125;95%CI = 1.10 - 1.41)、食管癌(SMR = 213;95%CI = 1.01 - 3.91)、结肠癌(SMR = 187;95%CI = 1.29 - 2.59)、肾癌(SMR = 2.08,95%CI = 1.00 - 3.82)、霍奇金病(SMR = 313;95%CI = 1.01 - 7.29)、肝硬化(SMR = 150;95%CI = 1.00 - 2.16)和自杀(SMR = 153;95%CI = 1.00 - 2.24)的死亡率均显著高于预期。所有事故的死亡率则显著低于预期(SMR = 53;95%CI = 0.34 - 0.79)。按警龄划分的死亡率显示,(1)警龄1至9年组的所有恶性肿瘤;(2)警龄10至19年组的全因、膀胱癌、白血病和动脉硬化性心脏病;以及(3)警龄超过30年组的结肠癌和肝硬化,死亡率均高于预期。文中讨论了这些研究结果的假设。