Hosokawa T, Ohta M, Koyama A, Saito K, Fine A
Hokkaido University School of Medicine, Sapporo, Japan.
Alcohol Clin Exp Res. 1998 Feb;22(1):60-6.
Optical methods can usefully augment classical techniques such as electrical recording for investigating cellular and network physiology. Here, recent developments in optical methods--including confocal and nonlinear fluorescence imaging, semiconductor array imaging, and improved fluorescent indicators of ion concentration and transmembrane electrical potential--are briefly reviewed, and examples are offered that may suggest potential applications to experimental studies in alcoholism research.
光学方法可有效地辅助诸如电记录等经典技术，用于研究细胞和网络生理学。在此，简要回顾了光学方法的最新进展，包括共聚焦和非线性荧光成像、半导体阵列成像，以及离子浓度和跨膜电势的改进型荧光指示剂，并给出了一些示例，这些示例可能为酒精中毒研究的实验性研究提示潜在的应用。
